The Chicago White Sox and the Seattle Mariners link up in an American League battle on Thursday afternoon. The Mariners have won three straight games and are on the verge of completing the sweep. Last night, Seattle defeated the White Sox, 8-6. Logan Gilbert (3-4, 3.45 ERA) is on the mound for the Mariners, while Shane Smith (3-7, 4.25 ERA) counters for Chicago.
First pitch from Steinbrenner Field is set for 4:10 p.m. ET. Seattle is a -290 favorite (risk $290 to win $100) in the latest White Sox vs. Mariners odds from DraftKings Sportsbook, while Chicago is a +229 underdog (risk $100 to win $229). The over/under for total runs scored is 7.5. Before making any White Sox vs. Mariners picks, be sure to see the MLB betting predictions from SportsLine’s proven model. Bet on Mariners vs. White Sox and every other MLB game at DraftKings, where you can get $200 in bonus bets after new users bet at least $5 with their first wager, in addition to more than $200 off NFL Sunday Ticket from YouTube and YouTube TV with the latest DraftKings promo code:
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 20 of the 2025 MLB season a profitable 28-23 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning nearly 60 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns.
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Here are the model’s three best bets for White Sox vs. Mariners on Thursday:
- Julio Rodriguez Under 1.5 total hits (-230)
- Josh Naylor Over 1.5 total bases (+125)
- Shane Smith Over 4.5 strikeouts (-115)`
Julio Rodriguez Under 1.5 total hits (-230)
Rodriguez leads the team in hits (120) with a .254 batting average, 21 home runs, and 62 RBI. DraftKings listed his total hits over/under at 1.5, but he has gone under that mark in seven of his last 10 outings. The model projects him to finish with 1.0 hits in this matchup.
Josh Naylor Over 1.5 total bases (+125)
Naylor owns a .290 batting average with 14 home runs and 65 RBI in 2025. DraftKings’ over/under for Naylor’s total bases is posted at 1.5. He’s cleared that number in three of his last five games. Last night, Naylor went 2-of-3 with a homer and two runs driven in. You can bet this prop at FanDuel, where you can get $150 in bonus bets with a winning wager of $5 or more with the latest FanDuel promo code:
Shane Smith Over 4.5 strikeouts (-115)
Smith takes the hill with 85 strikeouts on the season. DraftKings has his strikeout over/under set at 4.5, and he’s hit the over in nine of his last 15 games. On July 11, against the Cleveland Guardians, Smith tossed five Ks.
Want more MLB picks for Thursday?
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