UConn vs. Xaviers prediction, odds, time: 2026 college basketball picks from proven model

The third-ranked UConn Huskies look for the season sweep against the Xavier Musketeers in a key Big East Conference matchup on Tuesday. Xavier is coming off a 68-66 win over DePaul on Saturday, while Connecticut cruised to an 85-58 win at Creighton that same day. The Musketeers (12-10, 4-7 Big East), who are tied for sixth in the league, are 1-5 on the road this season. The Huskies (21-1, 11-0 Big East), who have won 17 in a row, are 11-1 on their home court.

Tipoff from PeoplesBank Arena in Hartford, Conn., is set for 7 p.m. ET. UConn leads the all-time series 8-5, including a 90-67 win at Xavier on Dec. 31. UConn is a 17.5-point favorite in the latest Xavier vs. UConn odds from DraftKings Sportsbook, while the over/under for total points scored is 147.5. Before making any UConn vs. Xavier picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and it enters Week 14 on a sizzling 10-1 run on its top-rated over/under college basketball picks dating back to last season, and is on an 8-1 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.    

Now, the model has simulated Xavier vs. UConn 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for UConn vs. Xavier:

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How to make Xavier vs. UConn picks

SportsLine’s model is going Over on the total (147.5 points). The Over has hit in eight of the last 10 head-to-head meetings between the schools. The Over has also hit in eight of the past 10 Xavier games and in six of the past 10 UConn games. 

The model projects the Musketeers to have four players register 10.2 points or more, including Tre Carroll’s projected 18.1 points. The Huskies, meanwhile, are projected to have five players score 12.8 or more points, led by Alex Karaban, who is projected to score 17.4 points. The model projects a combined total of 152 points as the Over clears in over 60% of simulations.

The model also says one side of the spread hits over 50% of the time. You can only see that pick at SportsLine.

So who wins UConn vs. Xavier, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the Xavier vs. Connecticut spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.