North Carolina vs. Syracuse prediction, odds, time: 2026 college basketball picks from proven model

The 16th-ranked North Carolina Tar Heels look to win their fourth game in a row when they battle the Syracuse Orange in a key ACC matchup on Monday. Syracuse is coming off an 86-72 win over Notre Dame on Saturday, while UNC defeated Georgia Tech 91-75 that same day. The Orange (13-9, 4-5 ACC), who are tied for 10th in the conference, are 2-2 on the road this season. The Tar Heels (17-4, 5-3 ACC), who are sixth in the conference, are 12-0 on their home floor this season.

Tipoff from the Dean E. Smith Center in Chapel Hill, N.C., is set for 7 p.m. ET. UNC leads the all-time series 18-7, and has won 14 of the last 17 meetings. North Carolina is an 11.5-point favorite in the latest Syracuse vs. North Carolina odds from DraftKings Sportsbook, while the over/under for total points scored is 156.5. Before making any North Carolina vs. Syracuse picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and it enters Week 13 on a sizzling 10-1 run on its top-rated over/under college basketball picks dating back to last season, and it is on a 6-0 roll on college basketball side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Now, the model has simulated Syracuse vs. North Carolina 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for UNC vs. Syracuse:

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How to make Syracuse vs. North Carolina picks

SportsLine’s model is going Under on the total (155.5 points). The Under has hit in three of the last eight head-to-head meetings between the schools.

The model projects the Orange to have five players register 10.5 points or more, including Donnie Freeman’s projected 15.9 points. The Tar Heels, meanwhile, are projected to have four players score 10 or more points, led by Caleb Wilson, who is projected to score 20.2 points. The model projects a combined total of 153 points as the Under clears in well over 50% of simulations.

The model also says one side of the spread hits nearly 60% of the time. You can only see that pick at SportsLine.

So who wins North Carolina vs. Syracuse, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the Syracuse vs. North Carolina spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.