The New England Patriots will host the New York Giants on ‘Monday Night Football,’ at 8:15 p.m. ET with the teams’ respective quarterbacks headlining the NFL DFS player pool. Drake Maye is an MVP contender as vets like Stefon Diggs and Hunter Henry have eased the learning curve in his second season. Meanwhile, Jaxson Dart can again be considered for daily Fantasy football lineups after missing the last few games. With an assortment of Giants injuries, Dart’s leaned on the likes of Tyrone Tracy and Theo Johnson, thus providing options for NFL DFS stacks.
You can’t forget about the under-the-radar players as potential MNF DFS picks, such as New York’s Isaiah Hodgins. He’s played just two games in 2025 but has 99 yards and a score across them. Finding players who outperform their price tags is a tried-and-true winning NFL DFS strategy. Before making any Patriots vs. Giants NFL DFS picks for ‘Monday Night Football,’ be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fantasy expert Mike McClure.
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McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings, including. In 2023, he finished tied for first in the DraftKings Millionaire Maker twice and the FanDuel Million once. Anyone who has followed him could be way up.
Now, McClure has turned his attention to ‘Monday Night Football’ and just locked in his top daily Fantasy football picks. You can only see his picks and analysis at SportsLine.
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Top NFL DFS picks for Patriots vs. Giants
One of McClure’s top NFL DFS picks for ‘Monday Night Football’ is Patriots quarterback Drake Maye. The sophomore signal caller entered Week 13 leading the NFL in passing yards while ranking seventh amongst quarterbacks in rushing yards. Now he gets to face a Giants defense which has allowed the second-most Fantasy points to QBs this season. Each of the last seven starting quarterbacks to face the Giants have had multiple total touchdowns, while Maye should be able to use his legs versus New York, which has allowed the most rushing yards to QBs. See who else to roster at SportsLine.
McClure is also rostering Giants receiver Wan’Dale Robinson who is coming off a 9-156-1 stat line, with the 156 receiving yards being a career high. Robinson already has surpassed his career high in receiving yards for the season and entered Week 13 with the 11th-most Fantasy points amongst wideouts. With New England having the No. 2 run defense, but ranking just 17th versus the pass, expect the Giants to heavily utilize the air game, which boosts Robinson’s NFL DFS value. See more NFL DFS picks at SportsLine.
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How to set Giants vs. Patriots NFL DFS lineups
McClure is targeting another undervalued player who could explode for huge numbers on ‘Monday Night Football’. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is, and the rest of McClure’s NFL DFS picks, at SportsLine.
So who is Mike McClure including in his optimal NFL DFS lineups for ‘Monday Night Football’, and which under-the-radar player offers huge value? Visit SportsLine now to see optimal NFL DFS picks, NFL DFS rankings, NFL DFS advice and NFL DFS stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.
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