The NBA takes center stage on Wednesday with nine more matchups. Three of them tip at 7 p.m. ET, with the last start coming at 10 p.m. ET. All three of the earliest tips have a spread of -2.5 or tighter, so they could all come down to the wire. The biggest mismatch is Thunder (-18.5) vs. Kings as OKC looks to move to 15-1 on the season.
Among the notable NBA odds include Rockets (-1.5) vs. Cavaliers, Knicks (-7.5) vs. Mavericks and Heat (-10.5) vs. Warriors, who won’t have Steph Curry (ankle) and have several other key players listed as questionable. That’s just one of the teams dealing with major injuries, so how should that impact your NBA betting strategy, and what are the best NBA bets today?
Before locking in any NBA picks, you’ll want to see the NBA predictions and betting advice from SportsLine’s proven computer model.
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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight seasons. The model enters Week 5 of the 2025-26 NBA season on a sizzling 28-13 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.
Now, the model has scoured the latest NBA odds and locked in three confident NBA best bets. If you successfully parlay its picks, you’d be looking at a payout of more than +700. You can only see the model’s NBA picks at SportsLine.
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Top NBA picks for Wednesday, Nov. 19
After simulating every game 10,000 times, the model is backing the Raptors (-2.5) to cover with room to spare against the Philadelphia 76ers in one of the 7 p.m. ET tips.
The Sixers are one of the teams dealing with significant injuries as Joel Embiid (knee) is listed as doubtful and Paul George (knee) has been ruled out. Toronto has all its major pieces and the model is projecting that Brandon Ingram, RJ Barrett, Scottie Barnes and Immanuel Quickley all score at least 16 points.
Toronto wins 120-112 in the simulations, covering the small spread in nearly 70% of simulations. See which other NBA parlay picks to make here, and bet that pick right here:
How to make NBA predictions for Wednesday, November 19
The model also has locked in two other strong picks, both on underdogs who are projected to win outright. You can only see the model’s NBA parlay at SportsLine.
What are the model’s top NBA parlay picks for Wednesday, and which best bets should you target for a chance at a payout of more than +700? Visit SportsLine now to see NBA best bets from a model that’s returned more than $10,000 on top-rated picks, and find out.
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