Mariners vs. Blue Jays MLB ALCS Game 2 predictions, line, odds, best bets by proven model

The Toronto Blue Jays will look to even their best-of-seven 2025 American League Championship Series when they battle the Seattle Mariners in Game 2 on Monday. Seattle opened the ALCS with a 3-1 victory on Sunday night. The Mariners (90-72), who won the AL West, are 41-43 on the road this season, including the postseason. The Blue Jays (94-68), who won the AL East, are 56-28 on their home field in 2025. Shortstop Bo Bichette (knee) is out for the Blue Jays.

First pitch from Rogers Centre in Toronto is set for 5:03 p.m. ET. The Blue Jays have won six of the past nine meetings with the Mariners. Toronto is a -123 favorite on the money line (risk $123 to win $100) in the latest Blue Jays vs. Mariners odds, with Seattle at +103 (risk $100 to win $103). The total number of runs Vegas thinks will be scored, or the over/under, is 8. Before making any Mariners vs. Blue Jays picks, be sure to be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model. 

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The SportsLine Projection Model simulates every MLB game 10,000 times. It enters the second week of the 2025 MLB playoffs a profitable 35-29 on top-rated MLB money-line picks this season. It has excelled making home run prop picks this season, returning nearly 30 units of profit. Anybody following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Mariners vs. Blue Jays and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Blue Jays vs. Mariners:

Why the Blue Jays can win

Toronto is expected to send right-hander Trey Yesavage (1-0, 3.21 ERA) to the mound. The 2024 first round draft pick by the Blue Jays started three games during the regular season and one in the postseason. In a 13-7 win over the New York Yankees in the ALDS, he pitched 5.1 innings, allowing no hits and one walk with 11 strikeouts. During the regular season, he pitched 14 innings, allowing 13 hits, five earned runs with seven walks and 16 strikeouts.

Among the Blue Jays’ leading hitters is right fielder George Springer. In 140 regular-season games, Springer hit .309 with 27 doubles, one triple, 32 homers, 84 RBI and 106 runs scored with 18 stolen bases. He has two homers and three RBI in five postseason games, including one homer in Game 1 of the series. In 96 career games against Seattle, he is hitting .262 with 23 doubles, two triples, 22 homers and 62 RBI. See which team to back at SportsLine.

Why the Mariners can win

Right-hander Logan Gilbert (6-6, 3.44 ERA) is expected to get the start for Seattle. In 25 games, all starts, during the regular season, he logged 131 innings, allowing 104 hits, 50 earned runs and 31 walks, while striking out 173. In two postseason games, including one start, he is 1-0 with a 1.13 ERA. In eight innings, he has allowed seven hits, one earned run and one walk, while striking out nine.

Cal Raleigh has carried the offense in the postseason, hitting .400 with a 1.163 OPS. First baseman Josh Naylor has also given the Mariners a boost. Since being acquired from the Arizona Diamondbacks midseason, he is hitting .299 with 10 doubles, nine homers and 33 RBI in 54 games. For the year, he is batting .295 with 20 homers, 92 RBI and 81 runs scored. He has six hits this postseason, including a 3-for-6 performance with a double and run scored in the 3-2 15-inning Game 5 win over the Detroit Tigers in the ALDS. See which team to back at SportsLine. 

How to make Mariners vs. Blue Jays picks

SportsLine’s model is leaning Over on the total, projecting 9.5 combined runs. It says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks. 

So who wins Mariners vs. Blue Jays, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.