Falcons vs. 49ers odds, picks, bets, predictions for ‘Sunday Night Football’ from proven model

The Atlanta Falcons (3-2) will visit the San Francisco 49ers (4-2) for a ‘Sunday Night Football’ showdown in NFL Week 7. The Falcons emerged from their Week 5 bye to upset the visiting Buffalo Bills 24-14. Meanwhile, the 49ers continued their injury-riddled season with a 30-19 Week 6 loss to the Tampa Bay Buccaneers. Brock Purdy (toe) and receiver Ricky Pearsall (knee) are among the players ruled out for San Francisco. Mac Jones is off the injury report and will start for the Niners at quarterback. George Kittle (hamstring) is also off the injury report.

Kickoff from Levi’s Stadium is set for 8:20 p.m. ET. San Francisco is a 1.5-point favorite in the latest Falcons vs. 49ers odds, and the over/under for total points scored is 47. Before making any 49ers vs. Falcons picks, be sure to see what the SportsLine projection model has to say. 

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The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 42-25 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.  

Now, the model has zeroed in on 49ers vs. Falcons. You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Falcons vs. 49ers on ‘Sunday Night Football’:

Why the Falcons can cover

Atlanta’s defense has quietly become one of the best in the NFL, leading the way with fewest total yards allowed (253.4) and fewest passing yards allowed (139.4). The Falcons are allowing 114.0 rushing yards, but will face a 49ers run game that has struggled mightily at the start of the season. Atlanta’s own run game, led by Bijan Robinson, is averaging 151.2 yards per game and could lead the way on Sunday against a San Francisco defense that has to figure out life without Fred Warner and Nick Bosa for the rest of the season. See which team to back at SportsLine. 

Why the 49ers can cover

Injuries continue to play a massive role for the 49ers, although getting Kittle back should be a big boost. San Francisco grinded out ugly wins against two good defenses in the Seattle Seahawks and Los Angeles Rams and stand at 3-3-0 ATS heading into Sunday. The defense is missing key pieces but should have an easier time pressuring Michael Penix Jr. than they did Baker Mayfield, as the Falcons QB has thrown four touchdowns and three interceptions and has been sacked seven times while totaling 59 sack yards lost. See which team to back at SportsLine. 

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How to make 49ers vs. Falcons picks

For ‘Sunday Night Football’ in NFL Week 7, the model is leaning under the total, and also says one side of the spread hits in well over 50% of simulations. See what it is at SportsLine.

Who wins Falcons vs. 49ers, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the 49ers vs. Falcons spread you need to jump, all from the model that is 42-25 on top-rated picks since 2024, and find out.