Cubs vs. Twins predictions, odds, line, start time: 2025 MLB picks, July 10 bets from proven model

The Chicago Cubs (54-38) and Minnesota Twins (45-47) finish their three-game series early Thursday afternoon. Chicago is on a two-game skid, falling 4-2 to the Twins last night. Meanwhile, Minnesota has won four of its previous five outings. Colin Rea (6-3, 4.13 ERA) gets the nod for the Cubs, while Chris Paddack (3-7, 4.64 ERA) takes the mound for Minnesota. 

First pitch from Target Field is set for 1:10 p.m. ET. Chicago is a -116 favorite on the money line (risk $116 to win $100) in the latest Twins vs. Cubs odds from FanDuel Sportsbook, while the over/under for total runs scored is 9.5. Before making any Cubs vs. Twins picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 16 of the 2025 MLB season 45-38 on top-rated MLB picks. It has excelled making home run prop picks this season, returning more than 28 units of profit. Anybody following at sportsbooks and on betting apps could have seen strong returns.

Now, the model has set its sights on Cubs vs. Twins and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Cubs vs. Twins, which you can get in on with a DraftKings promo code or a FanDuel promo code.

Why the Cubs can win

Outfielder Seiya Suzuki has great pop and power at the plate. The 30-year-old is first in the MLB in RBI (77) and sixth in home runs (25), to go along with a .259 batting average. On July 6 against the Cardinals, Suzuki was 2-of-5 with a double and a solo home run. 

First baseman Michael Busch provides Chicago with another offensive playmaker. Busch is leading the team in batting average (.297), along with 18 home runs and 56 RBI. He’s also sixth in the majors in OPS (.943). The 27-year-old enters this game on a five-game hitting streak. Busch went 1-of-3 in Wednesday’s contest. The Cubs have a 25-12 run line record following a loss. See which team to back at SportsLine.

Why the Twins can win

Left fielder Harrison Bader is batting .251 with 11 homers and 34 RBI. The 31-year-old has recorded a hit in four of his last six matchups. Back on Tuesday against Chicago, Bader was 2-of-4 with a two-run home run. 

Right fielder Trevor Larnach enters this game with a .253 batting average, 12 home runs, and 39 RBI. Additionally, he’s tied for first on the team in hits (80). Minnesota owns a 23-12 run line record as an underdog and is 6-1 in its last seven games at home. See which team to back at SportsLine. 

How to make Cubs vs. Twins picks

SportsLine’s model is leaning Over on the total, projecting 10.9 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks. 

So who wins Cubs vs. Twins, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.