Blue Jays vs. Orioles predictions, odds, line, start time: 2025 MLB picks, July 28 bets from proven model

An AL East contest has the Toronto Blue Jays (63-43) going on the road to begin a four-game series against the Baltimore Orioles (47-58) on Monday. The Detroit Tigers beat the Blue Jays 10-4 on Sunday, which ended their four-game win streak. Meanwhile, Baltimore has won two straight games. The Orioles defeated the Colorado Rockies 5-1 on July 27. Chris Bassitt (11-4, 3.88 ERA) is on the hill for Toronto. Zach Eflin (6-5, 5.78 ERA) will start for Baltimore. 

First pitch from Oriole Park at Camden Yards is set for 6:35 p.m. ET. Toronto is a -115 favorite on the money line (risk $115 to win $100) in the latest Blue Jays vs. Orioles odds from FanDuel Sportsbook, while the over/under for total runs scored is 9.5. Before making any Orioles vs. Blue Jays picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 19 of the 2025 MLB season a profitable 27-22 on top-rated MLB money-line picks. It has excelled making home run prop picks this season, returning more than 40 units of profit. Anybody following at sportsbooks and on betting sites could have seen strong returns.

Now, the model has set its sights on Blue Jays vs. Orioles and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are several MLB odds and betting lines for Blue Jays vs. Orioles, which you can get in on with a DraftKings promo code or a FanDuel promo code.

Why the Blue Jays can win

Right fielder George Springer is leading the team in home runs (18) with a .293 batting average and 57 RBI. He’s on a six-game hitting streak and has logged multiple hits in three consecutive games. On Sunday, he went 2-of-5 with one run driven in. 

Shortstop Bo Bichette is an athletic playmaker, logging .289 at the plate with 13 dingers and 65 RBI. In his previous outing, Bichette went 5-of-5 with two RBI. He has recorded a hit in nine straight matchups. See which team to back at SportsLine.

Why the Orioles can win

First baseman Ryan O’Hearn leads the team in both batting average (.282) and OBP (.375), along with 12 home runs. On Saturday’s win over the Rockies, he finished 2-of-5 with two singles and two RBI. This season, he also has 84 hits and 14 doubles. 

Right fielder Ramon Laureano has impressive power, leading the team in home runs (14) with 43 runs driven in and a .275 batting average. On Saturday against the Tigers, Laureano was 1-of-3 with a double. Baltimore has a 30-24 run line record as the underdog.  See which team to back at SportsLine. 

How to make Blue Jays vs. Orioles picks

SportsLine’s model is leaning Over on the total, projecting 9.7 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks. 

So who wins Blue Jays vs. Orioles, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.