Cincinnati vs. Houston prediction, odds, time, spread: 2026 college basketball picks from proven model

The 10th-ranked Houston Cougars go for the season sweep of the Cincinnati Bearcats when they meet in a Big 12 matchup on Saturday afternoon. Cincinnati is coming off a 67-57 win over Baylor on Wednesday, while Houston defeated TCU 79-70 that same night. The Bearcats (11-10, 3-5 Big 12), who are 1-4 against ranked opponents, are 0-5 on the road this season. The Cougars (18-2, 6-1 Big 12), who are 15-0 against unranked foes, are 10-0 on their home court.

Tip-off from the Fertitta Center in Houston is set for noon ET. Cincinnati leads the all-time series 33-18, but Houston is 7-0 against the Bearcats in games played at the Fertitta Center. Houston is a 14.5-point favorite in the latest Cincinnati vs. Houston odds from DraftKings Sportsbook, while the over/under for total points scored is 134.5. Before making any Houston vs. Cincinnati picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and it enters Week 13 on a sizzling 10-1 run on its top-rated over/under college basketball picks dating back to last season, and it is on a 6-0 roll on college basketball side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Now, the model has simulated Cincinnati vs. Houston 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for Houston vs. Cincinnati:

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How to make Cincinnati vs. Houston picks

SportsLine’s model is going Over on the total (134.5 points). The Over has hit in two of the last four Cincinnati games, and in each of the last three Houston games. The Bearcats are 6-4 against the spread in their last 10 games. The Cougars are 7-3 ATS in their last 10.

The model projects the Bearcats to have three players register 11.8 points or more, including Baba Miller’s projected 12.5 points. The Cougars, meanwhile, are projected to have three players score 13.2 or more points, led by Emanuel Sharp, who is projected to score 17.8 points. The model projects a combined total of 138 points as the Over clears in well over 60% of simulations.

The model also says one side of the spread hits nearly 60% of the time. You can only see that pick at SportsLine.

So who wins Houston vs. Cincinnati, and which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the Cincinnati vs. Houston spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.