Michigan vs. Michigan State prediction, odds, time, spread: 2026 college basketball picks from proven model

Two of the Big Ten’s top teams clash with first place on the line when the third-ranked Michigan Wolverines battle the seventh-ranked Michigan State Spartans on Friday night. Michigan is coming off a 75-72 win over Nebraska on Tuesday, while Michigan State defeated Rutgers 88-79 that same night. The Wolverines (19-1, 9-1 Big Ten), who are 4-0 against ranked opponents this season, are 5-0 on the road. The Spartans (19-2, 9-1 Big Ten), who are 3-2 against ranked foes, are 11-1 on their home court.

Tipoff from the Breslin Center in East Lansing, Mich., is set for 8 p.m. ET. Michigan leads the all-time series 104-92, but Michigan State holds a 56-38 edge on its home court. Michigan is a 1.5-point favorite in the latest Michigan vs. Michigan State odds from DraftKings Sportsbook, while the over/under for total points scored is 146.5. Before making any Michigan State vs. Michigan picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and it enters Week 13 on a sizzling 10-1 run on its top-rated over/under college basketball picks dating back to last season, and it is on a 6-0 roll on college basketball side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Now, the model has simulated Michigan vs. Michigan State 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for Michigan vs. Michigan State:

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How to make Michigan vs. Michigan State picks

SportsLine’s model is going Over on the total (146.5 points). The Over hit in Michigan State’s last game. The Wolverines are 3-7 against the spread in their last 10 games, while the Spartans are 6-4 ATS in their last 10.

The model projects the Wolverines to have three players register 10.5 points or more, including Yaxel Lendeborg’s projected 13.6 points. The Spartans, meanwhile, are projected to have four players score 10.6 or more points, led by Jeremy Fears Jr., who is projected to score 13.9 points. The model projects a combined total of 150 points as the Over clears in over 60% of simulations.

The model also says one side of the spread hits more than 70% of the time. You can only see that pick at SportsLine.

So who wins Michigan vs. Michigan State, and which side of the spread hits more than 70% of the time? Visit SportsLine now to see which side of the Michigan vs. Michigan State spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.