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Computer model locks in Bengals vs. Patriots picks, score prediction, SGP for NFL Week 12

Computer model locks in Bengals vs. Patriots picks, score prediction, SGP for NFL Week 12
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The Cincinnati Bengals and New England Patriots meet on Sunday in Week 12 of the 2025 NFL season with Cincinnati hoping to make a late playoff push while New England attempts to keep its winning streak going. The Bengals will be without Ja’Marr Chase thanks to a suspension, and quarterback Joe Burrow (toe) is out again. The Patriots have won eight in a row and have the No. 2 seed in the AFC but have the same record as the Broncos. 

Kickoff from Gillette Stadium is set for 1 p.m. ET on CBS and Paramount+. The Patriots are 6.5-point favorites in the latest SportsLine consensus odds and the total is 50.5. 

Click here to bet Bengals vs. Patriots at BetMGM Sportsbook, where new users get either $150 in bonus bets if your first bet wins or up to $1,500 in bonus bets if your first bet loses:

Where to bet on Bengals vs. Patriots 

Where to watch Bengals vs. Patriots on Sunday

When: Sunday, Nov. 23
Time: 1 p.m. ET
TV: CBS 
Stream: Paramount+
Follow along: CBS Sports App

Bengals vs. Patriots betting preview

Odds: Patriots -6.5, over/under 50.5

These teams met in Week 1 last season and the Patriots pulled off a surprising 16-10 win thanks to two crucial Cincinnati turnovers. A lot has changed since then. Mike Vrabel is the Patriots coach and Drake Maye is now the full-time starter in Year 2 looking like an MVP candidate, while Cincinnati has flailed thanks to injuries and poor defensive play.

Bengals vs. Patriots SGP

  • Patriots -6.5 (-110)
  • Over 50.5 (-115)
  • TreVeyon Henderson anytime touchdown scorer (-175)

Final odds: +343 at FanDuel (wager $100 to win $343)

Click here to bet Bengals vs. Patriots at FanDuel Sportsbook, where new users get $150 in bonus bets if their first bet of at least $5 wins:

Model’s Bengals vs. Patriots score prediction, picks

The Patriots cover the 6.5-point spread in 52% of model simulations, while the Over on 50.5 hits in 49% of simulations. However, the model does believe the Bengals are worth backing on the money line as they win in 32% of simulations. That brings bettors value at the current money line odds.

Bengals vs. Patriots score prediction: Patriots 30, Bengals 21

Want more Week 12 NFL picks?

You’ve seen the model’s best bets for Cincinnati Bengals vs. New England Patriots. Now, get against the spread, total and money-line picks for every Week 12 NFL game here, all from the model that’s simulated every game 10,000 times. 




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