Developing a successful NFL DFS strategy can take many forms, but one of the most common approaches is focusing on games with the highest projected point totals when identifying top NFL DFS picks and building NFL DFS stacks.The highest over/under in the Week 7 NFL odds for the Sunday main slate is 54.5 in the Cowboys vs. Commanders matchup. Other potential high-scoring matchups on Sunday include Colts vs. Chargers (over/under of 48.5), Saints vs. Bears (over/under of 46.5), and Raiders vs. Chiefs (over/under of 45.5). Thus, you can expect stars like Dak Prescott, Jayden Daniels, Jonathan Taylor, Ladd McConkey and Travis Kelce to be core players in many NFL DFS lineups.
Players of that caliber, however, will set back your NFL DFS salary cap, forcing you to search for more potential NFL DFS sleepers and NFL DFS values. Should players like Daniel Jones or Justin Herbert find their way into your quarterback slot for Sunday’s main slate? Will underperforming players like Saquon Barkley and Tua Tagovailoa finally live up to their price tags on NFL DFS sites? Before making any NFL DFS picks for Sunday or locking in NFL DFS lineups on sites like DraftKings and FanDuel, be sure to check out SportsLine’s advanced NFL DFS lineup optimizer.
New users can also target the latest Underdog promo code, where they can pick at Underdog and get $100 in site credits after making a $5 wager:
The DFS Optimizer uses info from the SportsLine Advanced-Data Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on betting apps like DraftKings and FanDuel. It simulates every game 10,000 times to help DFS players optimize and build winning DraftKings and FanDuel lineups. Optimize, export, and enter lineups confidently with injury updates, floor and ceiling player projections, and Vegas lines and picks all with one winning tool for sports betting apps.
Now, SportsLine’s NFL DFS Optimizer has turned its attention to Sunday’s 2025 NFL Week 6 schedule and just locked in its top daily Fantasy football lineups. You can only see its optimal lineups at SportsLine.
New users can get $50 in Pick6 credits at DraftKings when they play $5.
Top NFL Week 7 DFS picks for Sunday
One of the optimizer’s top DFS value picks for Sunday is Patriots quarterback Drake Maye ($6,300 on DraftKings and $8,200 on FanDuel). The former first-round pick out of North Carolina had a solid season as a rookie in 2024, as he threw for 2,276 yards with 15 touchdowns and 10 interceptions, and a passer rating of 88.1. He also added 421 rushing yards and two rushing touchdowns on 54 attempts, showcasing his mobility and poise under pressure.
In 2025, Maye has taken a big leap forward, throwing for 1,522 yards with 10 touchdowns and just two interceptions while completing over 73% of his throws. His improved accuracy and decision-making have helped the Patriots’ offense become more efficient and balanced. Maye has shown impressive command of the playbook and confidence in the pocket, cutting down on turnovers while still attacking downfield. See who else to pick here.
The optimizer’s NFL DFS strategy also includes rostering Cowboys running back Javonte Williams ($6,700 on DraftKings and $7,500 on FanDuel). The former second-round pick out of North Carolina signed with the Cowboys this past offseason after spending the first four years of his career with the Denver Broncos. Williams battled multiple injuries during his career in Denver, but still managed to rush for 2,394 yards and 11 touchdowns and catch 158 passes for 966 yards and five scores in 54 games.
Williams has enjoyed a resurgence in Dallas, totaling 92 carries for 476 yards and five touchdowns through six games. He’s also contributed 22 receptions for 83 yards and a receiving score, proving to be a reliable dual-threat option. Williams has shown renewed burst and confidence in the Dallas offense, thriving behind a strong offensive line. You can see the rest of the optimizer’s NFL DFS picks here.
New users can also check out the latest FanDuel promo code and get $300 in bonus bets instantly at FanDuel if your $5 bet wins.
How to build Sunday Week 7 NFL DFS lineups
The NFL DFS Optimizer is also targeting multiple undervalued players who could explode for huge numbers on Sunday. Those players could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who they are, and the rest of the optimizer’s NFL DFS picks, at SportsLine.
So what is the optimal NFL DFS lineup for Sunday, and which under-the-radar NFL DFS picks offer huge value? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice and stacks, all from an NFL DFS optimizer that simulates every game 10,000 times, and find out.
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